In the US, Methotrexate (methotrexate systemic) is a member of the following drug classes: antimetabolites, antipsoriatics, antirheumatics, other immunosuppressants and is used to treat Acute Lymphoblastic Leukemia, Acute Lymphocytic Leukemia, Acute Nonlymphocytic Leukemia, Bladder Cancer, Brain Tumor, Breast Cancer, Bullous Pemphigoid, Cervical Cancer, Choriocarcinoma, Cogan's Syndrome, Colorectal Cancer, Dermatomyositis, Ectopic Pregnancy, Eczema, Esophageal Carcinoma, Gastric Cancer, Graft-versus-host disease, Head and Neck Cancer, Hodgkin's Lymphoma, Lymphoma, Meningeal Leukemia, Mycosis Fungoides, Neoplastic Diseases, Non-Hodgkin's Lymphoma, Non-Small Cell Lung Cancer, Osteosarcoma, Ovarian Cancer, Pancreatic Cancer, Pemphigoid, Pemphigus, Pityriasis rubra pilaris, Psoriasis, Rheumatoid Arthritis, Small Cell Lung Cancer, Soft Tissue Sarcoma, Solid Tumors, Systemic Sclerosis, Trophoblastic Disease and Uveitis.
US matches:
- Methotrexate
- Methotrexate Tablets
- Methotrexate Sodium, Preservative Free injection
- Methotrexate injection
- Methotrexate Oral, Injection
- Methotrexate Sodium
- Methotrexate (Amethopterin; MTX)
UK matches:
- Methotrexate 25mg/ml solution for injection (hameln)
- Methotrexate 10 mg Tablets (Hospira UK Ltd) (SPC)
- Methotrexate 100 mg/ml Injection (Hospira UK Ltd) (SPC)
- Methotrexate 10mg tablets (SPC)
- Methotrexate 2.5 mg Tablets (Hospira UK Ltd) (SPC)
- Methotrexate 2.5 mg/ml Injection (Hospira UK Ltd) (SPC)
- Methotrexate 2.5mg tablets (SPC)
- Methotrexate 25 mg/ml Injection (Hospira UK Ltd) (SPC)
- Methotrexate 25mg/ml solution for Injection (SPC)
- Methotrexate Injection (SPC)
- Methotrexate Injection 100mg/ml (SPC)
- Methotrexate Tablet (SPC)
- Methotrexate Tablets B.P. 2.5mg (SPC)
- Methotrexate Tablets BP 10mg (SPC)
Scheme
Rec.INN
ATC (Anatomical Therapeutic Chemical Classification)
L01BA01,L04AX03
CAS registry number (Chemical Abstracts Service)
0000059-05-2
Chemical Formula
C20-H22-N8-O5
Molecular Weight
454
Therapeutic Categories
Immunosuppressant
Disease-modifying antirheumatic drug, DMARD
Antineoplastic agent, antimetabolite of folic acid
Chemical Names
(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid (IUPAC)
L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-
Foreign Names
- Methotrexatum (Latin)
- Methotrexat (German)
- Méthotrexate (French)
- Metotrexato (Spanish)
Generic Names
- Methotrexate (OS: BAN, JAN, USAN)
- Méthotrexate (OS: DCF)
- Metotrexato (OS: DCIT)
- Methylaminopterin (IS)
- MTX (IS)
- Methotrexat (PH: Ph. Eur. 6)
- Methotrexate (PH: BP 2010, Ph. Eur. 6, Ph. Int. 4, USP 32, JP XIV)
- Méthotrexate (PH: Ph. Eur. 6)
- Methotrexatum (PH: Ph. Int. 4, Ph. Eur. 6)
- Methotrexate Sodium (OS: BANM)
- Methotrexat disodium (IS)
- Methotrexate for Injection (PH: USP 32)
Brand Names
- Abitrexate
Pharmachemie, Taiwan; Teva, Israel; Teva Pharmaceuticals, South Africa
- Antifolan
Sindan, Romania
- Apo-Methotrexate
Apotex, Canada
- Artrait
TRB, Argentina
- Atrexel
Schering-Plough, Mexico
- Bendatrexat
Bendalis, Germany
- Biotrexate
Biochem, India
- DBL Methotrexate
Hospira, Australia; Hospira, Singapore
- Ebetrexat
Ebewe, Austria; Ebewe, Tunisia
- Emplex
Teva, Slovakia
- Emthex
Khandelwal, Myanmar
- Emthexate
Combiphar, Indonesia; Med, Turkey; Pharmachemie, Bangladesh; Pharmachemie, Indonesia; Pharmachemie, Sri Lanka; Pharmachemie, Malaysia; Pharmachemie, Taiwan
- Ervemin
Ivax, Argentina
- Ledertrexate
Biodim, France; Wyeth, Luxembourg
- Ledertrexato
Wyeth, Portugal
- Maxtrex
Pfizer, United Arab Emirates; Pfizer, Bahrain; Pfizer, Egypt; Pfizer, United Kingdom; Pfizer, Iraq; Pfizer, Iran; Pfizer, Jordan; Pfizer, Kuwait; Pfizer, Lebanon; Pfizer, Oman; Pfizer, Qatar; Pfizer, Saudi Arabia; Pfizer, Syria; Pfizer, Yemen
- Merex
Intas, Peru
- Metfogamma
Wörwag Pharma, Slovenia
- Methobion
Medicus, Greece
- Methoblastin
Pfizer, Australia
- Methotrax
Delta, Bangladesh
- Methotrexat APP
Abraxis, Switzerland
- Methotrexat Ebewe
Ebewe, Czech Republic; Ebewe, Georgia; Ebewe, Hungary; Ebewe, Indonesia; Ebewe, Israel; Ebewe, Lithuania; Ebewe, Latvia; Ebewe, Oman; Ebewe, Romania; Ebewe, Serbia; Ebewe, Slovenia; Ebewe, Tunisia; Ferron, Indonesia; OncoCorp, Germany
- Methotrexat Kohne
Kohne, Germany
- Methotrexat Lachema
Pliva, Hungary; Pliva, Russian Federation
- Methotrexat Merck
Merck Génériques, Tunisia
- Methotrexat
Lachema, Serbia; Pliva, Serbia
- Methotrexate Aeon
Aeon, Greece
- Méthotrexate Bellon
Sanofi-Aventis, France
- Methotrexate David Bull
png Gerolymatos, Greece
- Methotrexate DBL
Hospira, Australia; Hospira, Indonesia; Hospira, Singapore; Mayne, Malaysia; Orna, Turkey; Tempo Scan Pacific, Indonesia
- Methotrexate Ebewe
Ebewe, Hong Kong; Ebewe, Myanmar; Ebewe, Tunisia; Ebewe, Vietnam; InterPharma, New Zealand; Liba, Turkey
- Methotrexate Hospira
Hospira, Greece
- Methotrexate Injection BP
Hospira, New Zealand; PfizerPerth, Australia
- Methotrexate Injection
Mayne, Ireland
- Methotrexate Kalbe
Kalbe, Indonesia
- Methotrexate Lederle
Wyeth, Greece; Wyeth, South Africa
- Methotrexate Mayne Pharma
Medis, Slovenia
- Methotrexate Meda
Meda, Denmark
- Méthotrexate Merck
Mylan, France
- Méthotrexate Mylan
Mylan, France
- Methotrexate Orifarm
Orifarm, Denmark
- Methotrexate Orion
Orion, Sweden
- Methotrexate Paranova
Paranova, Denmark
- Methotrexate Pfizer
Pfizer, Denmark; Pfizer, Iceland; Pfizer, Philippines; Pfizer, Singapore
- Methotrexate Pharmacia
Pfizer, Vietnam
- Methotrexate Pliva
Pliva, Croatia (Hrvatska); Pliva, Slovenia
- Methotrexate Sandoz
Sandoz, Sweden
- Methotrexate SinGad
Singad, Denmark
- Methotrexate Teva
Med, Turkey; Teva, Hungary; Teva, Lithuania; Teva, Latvia; Teva, Sweden
- Méthotrexate Teva
Teva Santé, France
- Methotrexate Wyeth Lederle
Wyeth, Finland; Wyeth, Iceland
- Methotrexate Wyeth
Wyeth, Sweden; Wyeth, Singapore
- Methotrexate
Atafarm, Turkey; Aventis, Peru; Aventis, Tunisia; Baxter, New Zealand; Cyanamid, Oman; Goldshield, Ireland; Hospira, New Zealand; Lederle, Chile; Mylan, United States; Pfizer, Serbia; Remedica, Cyprus; Wyeth, Israel
- Methotrexat-Ebewe
Ebewe, Russian Federation
- Methotrexato
Pfizer, Ecuador; Pfizer, Venezuela
- Methotrexat-Teva
Teva, Czech Republic; Teva, Slovakia; Teva Pharma, Switzerland
- Meticil
Ivax, Peru
- Metoject
Medac, Czech Republic; Medac, Lithuania; Medac, Sweden; Onko-Koçsel, Turkey
- Metolate
Santen, Japan
- Metotrexate
Teva, Argentina
- Metotrexato Dosa
Dosa, Argentina
- Metotrexato Ebewe
Ebewe, Portugal
- Metotrexato Trixilem RU
Lemery, Peru
- Metotrexato Trixilem
Lemery, Peru
- Metotrexato
Baxter, Chile; Bestpharma, Chile; Induquimica, Peru; Kampar, Chile; Pfizer, Chile; Pfizer, Colombia; Pfizer, Peru; Tecnofarma, Peru
- Miantrex
Pfizer, Brazil
- MTX Hexal
Hexal, Luxembourg
- MTX medac
Medac, Germany
- MTX-Orion
Orion, Germany
- Neotrexat
NeoCorp, Germany
- Neotrexate
GlaxoSmithKline, India
- Novatrex
Wyeth, France
- P&U Methotrexate
Pfizer, South Africa
- Reumatrex
AC Farma, Peru
- Reutrexato
Apsen, Brazil
- Rheumatrex
Wyeth KK, Japan
- Tecnomet
Zodiac, Brazil
- Trexamette
Shiono Kemikaru, Japan
- Trexan
Orion, Finland; Orion, Hungary; Orion, Poland; Orion, Slovakia; Orion, Taiwan
- Trixate
Rontag, Argentina
- Trixilem
Chile, Chile
- Xantromid
Richmond, Argentina
- Zexate
Biogalenic, Venezuela; Dabur, Georgia; Dabur, Sri Lanka; Dabur, Myanmar; Dabur, Philippines
- Abitrexate
Abic, Romania; Teva, Israel
- Biometrox
Biosintética, Brazil
- Ebetrex
Nordic Drugs, Finland; Nordic Drugs, Sweden
- Ebetrexat
Ebewe, Austria
- Emthexat PF
Pharmachemie, Iceland
- Emthexate
Chemipharm, Greece; Pharmachemie, Netherlands; Teva, Belgium; Teva, Spain
- Lantarel
Wyeth, Germany
- Ledertrexate
Wyeth, Belgium; Wyeth, Mexico
- Medsatrexate
Asofarma, Mexico
- Metex
Medac, Germany
- Methoblastin
Pfizer, New Zealand
- Methotrexaat KrommeRijn
Kromme Rijn, Netherlands
- Methotrexaat PCH
Pharmachemie, Netherlands
- Methotrexaat Sandoz
Sandoz, Netherlands
- Methotrexat Ebewe
Ebewe, Poland; Ebewe Pharma, Slovakia; Sandoz, Switzerland
- Methotrexat Farmos
Orion, Switzerland
- Methotrexat Hexal
Hexal, Germany
- Methotrexat Lachema
Pliva, Czech Republic; Pliva, Hungary; Pliva, Slovakia
- Methotrexat Lederle
Wyeth, Austria; Wyeth, Czech Republic; Wyeth, Germany
- Methotrexat medac
Medac, Germany
- Methotrexat Proreo
ProReo Pharma, Switzerland
- Methotrexat Wyeth
Pfizer, Switzerland
- Methotrexat
Pliva Lachema, Poland
- Methotrexate Lederle
Wyeth, Thailand
- Methotrexate Sandoz
Sandoz, Sweden
- Methotrexate Sodium for Injection
Bedford, United States
- Methotrexate Sodium Injection
Mayne, United States
- Methotrexate Sodium
APP, United States; Bedford, United States; Dava, United States; Ebewe, United States; Generamedix, United States; Hospira, Canada; Hospira, United States; Mylan, United States; Pharmachemie, United States; Roxane, United States; Teva USA, United States; Wyeth, Taiwan
- Methotrexate Teva
Teva, Sweden
- Methotrexate Wyeth
Wyeth, Greece; Wyeth, Sweden
- Methotrexate
Aventis, Peru; Teva, Norway; Wyeth, Canada; Wyeth, Italy; Wyeth, Norway; Wyeth, Taiwan
- Methotrexat-GRY
Teva-Gry, Germany
- Metoject
Euro, Netherlands; Fannin, Ireland; Gebro, Switzerland; Gebro, Spain; Medac, Austria; Medac, Denmark; Medac, Estonia; Medac, Finland; Medac, United Kingdom; Medac, Greece; Medac, Hungary; Medac, Latvia; Medac, Netherlands; Medac, Norway; Medac, Sweden; Medac, Slovenia; Medac, Slovakia; Medcor, Netherlands; Medexus, Canada; Nordic, France; Top Pharma, Netherlands
- Metotab
Medac, Sweden
- Metotreksat
Pliva, Bosnia & Herzegowina; Wyeth, Slovenia
- Metotressato Teva
Teva, Italy
- Metotrexato Asofarma
Raffo, Argentina
- Metotrexato Filaxis
Filaxis, Argentina; Filaxis, Peru
- Metotrexato Hopira
Mayne, Italy
- Metotrexato Lederle
D.A.C., Iceland
- Metotrexato Martian
LKM, Argentina
- Metotrexato Merck
Merck Genericos, Spain
- Metotrexato Microsules
LKM, Argentina
- Metotrexato Pfizer
Pfizer, Spain
- Metotrexato Wyeth
Wyeth, Spain
- Metotrexato
Pfizer, Chile
- MTX Hexal
Hexal, Germany
- MTX Sandoz
Sandoz, Germany
- MTX-dura
Mylan dura, Germany
- Otaxem
Best, Mexico
- ratio-Methotrexate
ratiopharm, Canada
- Trexan
Atafarm, Turkey; Orion, Estonia
International Drug Name Search
Glossary
| BAN | British Approved Name |
| BANM | British Approved Name (Modified) |
| DCF | Dénomination Commune Française |
| DCIT | Denominazione Comune Italiana |
| IUPAC | International Union of Pure and Applied Chemistry |
| IS | Inofficial Synonym |
| JAN | Japanese Accepted Name |
| OS | Official Synonym |
| PH | Pharmacopoeia Name |
| Rec.INN | Recommended International Nonproprietary Name (World Health Organization) |
| SPC | Summary of Product Characteristics (UK) |
| USAN | United States Adopted Name |
Click for further information on drug naming conventions and
International Nonproprietary Names.
